<p>The bar graphs (mean±SD) represent the cell distribution in the peri-infarct, transition and core regions <b>A</b>) the percentage of total cell number per region and <b>B-D</b>) the number of cells/µm<sup>2</sup>, <b>B’</b>) activated microglia (Iba1), <b>C’</b>) proliferating cells (BrdU) and <b>D’</b>) reactive astrocytes (GFAP). No GFAP positive cells were observed in the core region. Sulforaphane treatment only altered the microglial cell number in the peri-infarct region compared to vehicle treatment (F(2,15) = 4.76, <i>p</i>≤0.025) (<i>n</i> = 5–9 in each group, solid black box GFAP astrocytes, solid grey box Iba1 microglia, open box BrdU proliferating cells).</p
Reactive gliosis is a hallmark of brain pathology and the injury response, yet the extent to which a...
(a) Stitched image of coronal section showing microglial density at steady state (Ctrl), after 2 wee...
<p><b>Fluorescence labeling of the immune cell markers CD68 and Iba combined with GFAP-immunodetecti...
<p>Immunohistochemical images of GFAP positive astrocytes of a quiescent appearance found within the...
<p><b>(A-B)</b> Representative images of microglia/macrophage activation, as shown by ED1 (green) an...
<p><b><i>A</i></b>, Brain sections showing the increasing number and different distribution of EGFP<...
<p><b>(A)</b> TTC-stained brain section indicating the stroke area (pale color marked by asterisk). ...
<p>(A) Images of IHC for reactive astrocyte marker GFAP on ipsilateral hemisphere at 7 days (top two...
<p><b>A</b>) Proliferating cells were the most abundant at 3 day post injury (dpi), as revealed by s...
<p>Oligodendroglia and other olig2+ glia were identified with antibodies to NG2 (A), olig2 (B) and K...
<p>) <i>(left panel)</i> The distribution of GFAP-expressing reactive astrocytes in response to a ne...
<p>A: GFAP immunostained astrocytes in dissociated mixed hippocampal cell cultures after 8 cycles of...
<p>Scatter plots of proliferating SVZ cells (Ki67+) from sham-operated (<i>n</i> = 3), 7 day post-st...
<p>A: Representative cytometry data showing the purity of microglia isolated. Of the isolated cells,...
<p>The graphs in (a) compare the mean total cell density (left) and the mean MIB-1 positive cell den...
Reactive gliosis is a hallmark of brain pathology and the injury response, yet the extent to which a...
(a) Stitched image of coronal section showing microglial density at steady state (Ctrl), after 2 wee...
<p><b>Fluorescence labeling of the immune cell markers CD68 and Iba combined with GFAP-immunodetecti...
<p>Immunohistochemical images of GFAP positive astrocytes of a quiescent appearance found within the...
<p><b>(A-B)</b> Representative images of microglia/macrophage activation, as shown by ED1 (green) an...
<p><b><i>A</i></b>, Brain sections showing the increasing number and different distribution of EGFP<...
<p><b>(A)</b> TTC-stained brain section indicating the stroke area (pale color marked by asterisk). ...
<p>(A) Images of IHC for reactive astrocyte marker GFAP on ipsilateral hemisphere at 7 days (top two...
<p><b>A</b>) Proliferating cells were the most abundant at 3 day post injury (dpi), as revealed by s...
<p>Oligodendroglia and other olig2+ glia were identified with antibodies to NG2 (A), olig2 (B) and K...
<p>) <i>(left panel)</i> The distribution of GFAP-expressing reactive astrocytes in response to a ne...
<p>A: GFAP immunostained astrocytes in dissociated mixed hippocampal cell cultures after 8 cycles of...
<p>Scatter plots of proliferating SVZ cells (Ki67+) from sham-operated (<i>n</i> = 3), 7 day post-st...
<p>A: Representative cytometry data showing the purity of microglia isolated. Of the isolated cells,...
<p>The graphs in (a) compare the mean total cell density (left) and the mean MIB-1 positive cell den...
Reactive gliosis is a hallmark of brain pathology and the injury response, yet the extent to which a...
(a) Stitched image of coronal section showing microglial density at steady state (Ctrl), after 2 wee...
<p><b>Fluorescence labeling of the immune cell markers CD68 and Iba combined with GFAP-immunodetecti...