<p>The observation period (days) is from 18 months (+/−6 months) after initiation of cART till death or 01/01/2010. The dotted line depicts the highest 50<sup>th</sup> percentile and the full line depicts the lowest 50<sup>th</sup> percentile. Analysis of survival linked to T cell subset are made with proportions of CD4+ and CD8+ cells respectively. Analysis using concentrations instead of proportions yielded similar results. Subsets were defined as naïve CD4/8(CD45RA+, CD62+), memory CD4/8 (CD45RA-, CD45R0+) and activated CD4 (HLA-DR+), and activated CD8 (HLA-DR+, CD38+).</p
<p>(A) CD38 and Ki67 co-expressing cells in the total CD8 T cell population over time in one represe...
<p>Disease-specific Kaplan-Meier survival estimates based on the levels of CD4<sup>+</sup>CD25<sup>h...
<p>(a) Survival curves of the low density (n = 70) vs. high density (n = 73) groups of CD8+ TILs in ...
<p>Mean values of circulating CD4+ and CD8+ T-cell percentages as a function of years since cART ini...
<p>Kaplan-Meier plots showing time taken to achieve CD4 counts >500cells/µl among (A) patients in...
<p>*p-values determined using Mann–Whitney U-tests. Subsets of CD4<sup>+</sup> T cells are presented...
<p>A histograms of the expression of Ki-67 in the overall CD8 T-cell population and tetramer<sup>+</...
<p>Legends: green line: HHV-8 negative; blue line: HHV-8 positive green; +: HHV-8 negative censored ...
<p>Kaplan-Meier plots showing mortality of 435 patients after initiation of ART by baseline WHO clin...
<p>The patients were stratified into two groups based on the median of the T cell proportion among t...
<p>(<b>A</b>) PTK7 survivorship functions. Black lines: estimated survivorship using best-fit parame...
<p>Kaplan-Meier survival curve shows the prognostic effect of CD8-negative, CD8+/TIA-1- and CD+8/TIA...
D4+ T cells were subdivided into the main T cell subsets using CD45RA and CCR7. (C) The CD45RA+CCR7+...
<p>A) Total CD4<sup>−</sup>CD8<sup>−</sup> cells expressed as a % of CD45RA<sup>+</sup> cells (left ...
D8+ T cells were subdivided into the main T cell subsets using CD45RA and CCR7. (C) The CD45RA+CCR7+...
<p>(A) CD38 and Ki67 co-expressing cells in the total CD8 T cell population over time in one represe...
<p>Disease-specific Kaplan-Meier survival estimates based on the levels of CD4<sup>+</sup>CD25<sup>h...
<p>(a) Survival curves of the low density (n = 70) vs. high density (n = 73) groups of CD8+ TILs in ...
<p>Mean values of circulating CD4+ and CD8+ T-cell percentages as a function of years since cART ini...
<p>Kaplan-Meier plots showing time taken to achieve CD4 counts >500cells/µl among (A) patients in...
<p>*p-values determined using Mann–Whitney U-tests. Subsets of CD4<sup>+</sup> T cells are presented...
<p>A histograms of the expression of Ki-67 in the overall CD8 T-cell population and tetramer<sup>+</...
<p>Legends: green line: HHV-8 negative; blue line: HHV-8 positive green; +: HHV-8 negative censored ...
<p>Kaplan-Meier plots showing mortality of 435 patients after initiation of ART by baseline WHO clin...
<p>The patients were stratified into two groups based on the median of the T cell proportion among t...
<p>(<b>A</b>) PTK7 survivorship functions. Black lines: estimated survivorship using best-fit parame...
<p>Kaplan-Meier survival curve shows the prognostic effect of CD8-negative, CD8+/TIA-1- and CD+8/TIA...
D4+ T cells were subdivided into the main T cell subsets using CD45RA and CCR7. (C) The CD45RA+CCR7+...
<p>A) Total CD4<sup>−</sup>CD8<sup>−</sup> cells expressed as a % of CD45RA<sup>+</sup> cells (left ...
D8+ T cells were subdivided into the main T cell subsets using CD45RA and CCR7. (C) The CD45RA+CCR7+...
<p>(A) CD38 and Ki67 co-expressing cells in the total CD8 T cell population over time in one represe...
<p>Disease-specific Kaplan-Meier survival estimates based on the levels of CD4<sup>+</sup>CD25<sup>h...
<p>(a) Survival curves of the low density (n = 70) vs. high density (n = 73) groups of CD8+ TILs in ...