Identification of RETN, TFF1 and FCRL5 as genes with expression levels that correlate with frequencies of T_H17 and T_Reg cells.

<p>(A) The frequency of T_H17 cells was used as a quantitative variable to identify gene probes with correlated expression values using significance analysis of microarrays (SAM). Gene probes in red are positively correlated and gene probes in green are negatively correlated with T_H17 cell frequency at a FDR of 0%. (B) Identification of gene probes correlated with frequency of CD4⁺CD25⁺FoxP3⁺ T_Reg cells. C) Real time PCR analysis of 40 biopsy samples confirms the positive correlation between T_H17 cells with RETN expression, the negative correlation between T_H17 cells with TFF1 expression, and the positive correlation between T_Reg cells with FCRL5 expression.