We have developed a comprehensive resource devoted to biologists wanting to optimize the use of gene trap clones in their experiments. We have processed 300 602 such clones from both public and private projects to generate 28 199 'UniTraps', i.e. distinct collections of unambiguous insertions at the same subgenic region of annotated genes. The UniTrap resource contains data relative to 9583 trapped genes, which represent 42.3% of the mouse gene content. Among the trapped genes, 7 728 have a counterpart in humans, and 677 are known to be involved in the pathogenesis of human diseases. The aim of this analysis is to provide the wet lab researchers with a comprehensive database and curated tools for (i) identifying and comparing the clones car...
In an effort to make transgenesis more flexible and reproducible, we developed a system based on nov...
A major task in the second phase of the genome sequencing projects is the identification of coding s...
High-throughput gene trapping is a random approach for inducing insertional mutations across the mou...
We have developed a comprehensive resource devoted to biologists wanting to optimize the use of gene...
We have developed a comprehensive resource devoted to biologists wanting to optimize the use of gene...
Gene trapping is a method of generating murine embryonic stem (ES) cell lines containing insertional...
Gene trapping is a method of generating murine embryonic stem (ES) cell lines containing insertional...
Gene trapping is a method of generating murine embryonic stem (ES) cell lines containing insertional...
Gene trapping is a method of generating murine embryonic stem (ES) cell lines containing insertional...
Gene trapping is a method of generating murine embryonic stem (ES) cell lines containing insertional...
High-throughput gene trapping is a random approach for inducing insertional mutations across the mou...
A major challenge of the postgenomic era is the functional characterization of every single gene wit...
A major challenge of the postgenomic era is the functional characterization of every single gene wi...
AbstractThe gene trap methodology is a powerful tool to characterize novel genes and analyze their i...
Gene trapping is a high-throughput approach that has been used to introduce insertional mutations in...
In an effort to make transgenesis more flexible and reproducible, we developed a system based on nov...
A major task in the second phase of the genome sequencing projects is the identification of coding s...
High-throughput gene trapping is a random approach for inducing insertional mutations across the mou...
We have developed a comprehensive resource devoted to biologists wanting to optimize the use of gene...
We have developed a comprehensive resource devoted to biologists wanting to optimize the use of gene...
Gene trapping is a method of generating murine embryonic stem (ES) cell lines containing insertional...
Gene trapping is a method of generating murine embryonic stem (ES) cell lines containing insertional...
Gene trapping is a method of generating murine embryonic stem (ES) cell lines containing insertional...
Gene trapping is a method of generating murine embryonic stem (ES) cell lines containing insertional...
Gene trapping is a method of generating murine embryonic stem (ES) cell lines containing insertional...
High-throughput gene trapping is a random approach for inducing insertional mutations across the mou...
A major challenge of the postgenomic era is the functional characterization of every single gene wit...
A major challenge of the postgenomic era is the functional characterization of every single gene wi...
AbstractThe gene trap methodology is a powerful tool to characterize novel genes and analyze their i...
Gene trapping is a high-throughput approach that has been used to introduce insertional mutations in...
In an effort to make transgenesis more flexible and reproducible, we developed a system based on nov...
A major task in the second phase of the genome sequencing projects is the identification of coding s...
High-throughput gene trapping is a random approach for inducing insertional mutations across the mou...