<p>Mechanistically, tumor oxygenation results from an balance between oxygen delivery (perfusion) and local oxygen consumption (which depends on the cellular viability and mitochondrial respiration) (Adapted from <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0040772#pone.0040772-Gallez1" target="_blank">[7]</a>).</p
Oxygen supports the life of all aerobic organisms and virtually every cell type is capable of sensin...
Tumor hypoxia has long been considered as a detrimental factor for the response to irradiation. In o...
Copyright: © Guido et al. This is an open-access article distributed under the terms of the Creativ...
). Our goals were (i) to evaluate the contribution of the “oxygen effect” to the radiosensitizing ef...
Endogenous mechanisms of reactive oxygen (ROS) and nitrogen species production and of antioxidant de...
Response to cancer treatment is largely influenced by the tumor microenvironment. One of the most im...
Peroxiredoxins (Prxs) are a class of ubiquitous peroxidases that degrade hydrogen peroxide. They are...
Background: Paclitaxel (PTX) is a potent anti-cancer chemotherapeutic agent and is widely used in th...
The concept of hypoxia and its role in tumor therapy are currently under re-evaluation. Poor oxygena...
BACKGROUND: Paclitaxel (PTX) is a potent anti-cancer chemotherapeutic agent and is widely used in th...
Tumor oxygenation is a key factor of the radiotherapy treatment efficacy because the efficacy for ki...
We hypothesized that nonsteroidal antiinflammatory drugs (NSAIDs) might enhance tumor radiosensitivi...
<p>Oxygen rate measured as function of time (mean ± SEM). Slope for treated mice (<i>n</i> = 3) sign...
The unique metabolism of tumors was described many years ago by Otto Warburg, who identified tumor c...
<div><p>Tumor hypoxia is one of the most important parameters that determines treatment sensitivity ...
Oxygen supports the life of all aerobic organisms and virtually every cell type is capable of sensin...
Tumor hypoxia has long been considered as a detrimental factor for the response to irradiation. In o...
Copyright: © Guido et al. This is an open-access article distributed under the terms of the Creativ...
). Our goals were (i) to evaluate the contribution of the “oxygen effect” to the radiosensitizing ef...
Endogenous mechanisms of reactive oxygen (ROS) and nitrogen species production and of antioxidant de...
Response to cancer treatment is largely influenced by the tumor microenvironment. One of the most im...
Peroxiredoxins (Prxs) are a class of ubiquitous peroxidases that degrade hydrogen peroxide. They are...
Background: Paclitaxel (PTX) is a potent anti-cancer chemotherapeutic agent and is widely used in th...
The concept of hypoxia and its role in tumor therapy are currently under re-evaluation. Poor oxygena...
BACKGROUND: Paclitaxel (PTX) is a potent anti-cancer chemotherapeutic agent and is widely used in th...
Tumor oxygenation is a key factor of the radiotherapy treatment efficacy because the efficacy for ki...
We hypothesized that nonsteroidal antiinflammatory drugs (NSAIDs) might enhance tumor radiosensitivi...
<p>Oxygen rate measured as function of time (mean ± SEM). Slope for treated mice (<i>n</i> = 3) sign...
The unique metabolism of tumors was described many years ago by Otto Warburg, who identified tumor c...
<div><p>Tumor hypoxia is one of the most important parameters that determines treatment sensitivity ...
Oxygen supports the life of all aerobic organisms and virtually every cell type is capable of sensin...
Tumor hypoxia has long been considered as a detrimental factor for the response to irradiation. In o...
Copyright: © Guido et al. This is an open-access article distributed under the terms of the Creativ...