Effects of sleep deprivation on sleep recovery and EEG delta power changes during NREM sleep.

<p>(A) Time-course changes in NREM sleep (NREMS) and REM sleep (REMS) and the delta power of slow-wave activity (0.5–5 Hz) during NREM sleep are expressed as the 2 h means ± SEM during baseline recordings (closed circles) and sleep deprivation (SD, open circles) in NAB (n = 7), LAB (n = 10), HAB (n = 10) mice. SD began at the onset of the light period and lasted for 6 h. Two-way ANOVA among the three mouse lines revealed a significant effect of ‘line’ on EEG delta power in NREM sleep during the post-SD 6–12 h during the light period (<i>P</i><0.001) and on NREM and REM sleep and EEG delta power during the post-SD 13–18 h during the dark period (<i>P</i><0.05, <i>P</i><0.05, <i>P</i><0.001). * <i>P</i><0.05, ** <i>P</i><0.001, assessed by two-way ANOVA with the factors ‘line’ and ‘interval’ followed by Bonferroni's test.