MiR-107 suppressed the differentiation of EPCs.

<p>(<b>1</b>) Upregulation of miR-107 suppressed the differentiation of EPCs.CD31 (a) and eNOS (b and c) expression of EPCs were determined after up-regulation of miR107. (*p<0.05 between groups). [N: EPCs cultured under normoxic conditions; L: EPCs cultured under hypoxic conditions; N+H: EPCs infected with Lentiviral vector expressing miR107 and cultured under normoxic conditions; L+H: EPCs infected with Lentiviral vector expressing miR107 and cultured under hypoxic conditions.] (<b>2</b>) Downregulation of miR-107 promoted the differentiation of EPCs.CD31 (d) and eNOS (e and f) expression of EPCs were determined after inhibition of miR107. [N: EPCs cultured under normoxic conditions; L: EPCs cultured under hypoxic conditions; N+L: EPCs transfected with miR-107 inhibitor and cultured under normoxic conditions; L+L: EPCs transfected with miR-107 inhibitor and cultured under hypoxic conditions. (*p<0.05 between groups)].