Survival after myocardial infarction.

<p>Kaplan-Meier survival analysis of rats with acute myocardial infarction. *p<0.05 vs. LETO. 4-PBA = pretreatment with 4-PBA at dose of 40 mg/kg/day; 4-PBA80 = pretreatment with 4-PBA at a dose of 80 mg/kg/day; Cyclosporine A = pretreatment with cyclosporine A at dose of 20 mg/kg/day; TUDCA = pretreatment with sodium tauroursodeoxycholic acid (100 mg/kg/day). All agents were administered intraperitoneally for 7 days before infarct experiments. Experiments using TUDCA and a higher dose of 4-PBA (i.e., 4-PBA80 group) were additionally performed as <i>post-hoc</i> experiments.