IFP and vascular density.

<p>Fluorescence images showing vascular networks of A-07-GFP (<b>A</b>) and R-18-GFP (<b>B</b>) tumors representing low (upper panel), intermediate (middle panel), and high (lower panel) IFP values. Scale bars, 1 mm. <b>C–E</b>) IFP versus vascular density calculated as vascular area fraction (<b>C</b>), total vessel density (<b>D</b>), and density of large vessels (density of vessels with diameter >20 µm) (<b>E</b>). Points represent individual A-07-GFP (•) and R-18-GFP (Δ) tumors. Lines represent linear regression curves. Solid lines, P<0.05; dotted lines, P>0.05.