Mucin isoforms are degraded and MUC2 mRNA is up-regulated during intestinal ischemia.

<p>Western blot for mucin 2 and mucin 13 in jejunal homogenates of SHAM animals or animals subjected to SAO protocol with luminal inhibition with acarbose (ACA), tranexamic acid (TA) or nafamostat mesilate or without (NI) (<b>A</b>). Density levels measurement of mucin 2 (<b>B</b>) and mRNA expression of MUC2 (<b>C</b>). Mucin 13 density levels of different fragments (<b>D</b>). Values are mean±SEM (n = 4)/group **P<0.001 compared to SHAM, †††P<0.0001 compared to SAO30, ‡P<0.05 and ‡‡P<0.001 compared to ACA.