<p>Effects of AS-IV on podocyte apoptosis detected by TUNEL assay (A), caspase-3 activity (B) and cleaved caspase-3 protein expression (C) in diabetic rats at 12 weeks after STZ injection. Results are expressed are the means ± SD. *<i>P</i><0.05 vs NC. <sup>#</sup><i>P</i><0.05 vs DN.</p
<p>Effects of AS-IV on cleaved caspase-3 protein expression (A), and mRNA expression of Bax (B) and ...
<p>Diabetes was induced by single intraperitoneal injection of STZ (65 mg/kg). Mice were treated wit...
Glycogen synthase kinase-3β (GSK-3β) is involved in the pathogenesis of various kidney diseases. Thi...
<p>Effects of AS-IV on apoptosis assessed by Hoechst staining (A) and FACS (B), ROS production (C) a...
<p>AS-IV treatment (2.5, 5, 10 mg·kg<sup>−1</sup>·d<sup>−1</sup>) was started 2 weeks before STZ inj...
Glucose-induced reactive oxygen species (ROS) production initiates podocyte apoptosis, which represe...
<p>Effects of AS-IV on glomerular ultrastructure (A) and albuminuria in diabetic rats at 4 weeks (B)...
Background: Endoplasmic reticulum (ER) stress-induced podocyte apoptosis plays a critical role in th...
<p>Effects of AS-IV on protein expression of Bax and Bcl-2 (A), as well as mRNA expression of Bax (B...
Xiao Lei, Limei Zhang, Zonglin Li, Jigang Ren Traditional Chinese Medicine Department, Affiliated H...
<p>Diabetes was induced by single intraperitoneal injection of STZ (65 mg/kg). Mice were treated wit...
<p>Two months post diabetes induction or age matched normal rats were assessed for apoptosis by TUNE...
<p>A. Detection of apoptosis by TUNEL assay in different groups. Percentage of TUNEL positive cells ...
The aim of the study was to determine in a rat model of streptozotocin-induced diabetic nephropathy ...
Background. Diabetic nephropathy (DN) is one of the leading causes of end-stage kidney disease. Rece...
<p>Effects of AS-IV on cleaved caspase-3 protein expression (A), and mRNA expression of Bax (B) and ...
<p>Diabetes was induced by single intraperitoneal injection of STZ (65 mg/kg). Mice were treated wit...
Glycogen synthase kinase-3β (GSK-3β) is involved in the pathogenesis of various kidney diseases. Thi...
<p>Effects of AS-IV on apoptosis assessed by Hoechst staining (A) and FACS (B), ROS production (C) a...
<p>AS-IV treatment (2.5, 5, 10 mg·kg<sup>−1</sup>·d<sup>−1</sup>) was started 2 weeks before STZ inj...
Glucose-induced reactive oxygen species (ROS) production initiates podocyte apoptosis, which represe...
<p>Effects of AS-IV on glomerular ultrastructure (A) and albuminuria in diabetic rats at 4 weeks (B)...
Background: Endoplasmic reticulum (ER) stress-induced podocyte apoptosis plays a critical role in th...
<p>Effects of AS-IV on protein expression of Bax and Bcl-2 (A), as well as mRNA expression of Bax (B...
Xiao Lei, Limei Zhang, Zonglin Li, Jigang Ren Traditional Chinese Medicine Department, Affiliated H...
<p>Diabetes was induced by single intraperitoneal injection of STZ (65 mg/kg). Mice were treated wit...
<p>Two months post diabetes induction or age matched normal rats were assessed for apoptosis by TUNE...
<p>A. Detection of apoptosis by TUNEL assay in different groups. Percentage of TUNEL positive cells ...
The aim of the study was to determine in a rat model of streptozotocin-induced diabetic nephropathy ...
Background. Diabetic nephropathy (DN) is one of the leading causes of end-stage kidney disease. Rece...
<p>Effects of AS-IV on cleaved caspase-3 protein expression (A), and mRNA expression of Bax (B) and ...
<p>Diabetes was induced by single intraperitoneal injection of STZ (65 mg/kg). Mice were treated wit...
Glycogen synthase kinase-3β (GSK-3β) is involved in the pathogenesis of various kidney diseases. Thi...