AS-IV restored the balance of Bax and Bcl-2 mRNA and protein expression in diabetic rats.

<p>Effects of AS-IV on protein expression of Bax and Bcl-2 (A), as well as mRNA expression of Bax (B) and Bcl-2 (C) in diabetic rats at 12 weeks after STZ injection. The protein expression of Bax and Bcl-2 was examined by Western blotting. The mRNA expression of Bax and Bcl-2 was examined by Real-time RT-PCR. Results are expressed are the means ± SD. *<i>P</i><0.05 vs NC. ^#<i>P</i><0.05 vs DN.