<p>Note that the parameters relating to membrane cycling of the three GTPases are not included due to their undetermined nature. The primary role of these parameters is to determine the quasi steady state fraction of membrane attached GTPases, which we instead account for by varying the composite parameter .</p
Values of the model parameters used to fit the molecular permeability and the TER model.</p
<p>Typical parameter values used in the simulations are shown. For parameters that were varied, the ...
<div><p>(A) The Rho family of GTPases, which are localized in the membrane (GTP-bound active forms) ...
<p>The asterisk represents the product between binding rates and concentration of GDI (subscripts th...
<p>A. Model for lumped variables and rates. The term in the dotted box includes effector bound GTPas...
<p>These parameters were fixed throughout our simulations.</p><p>Default parameter values for the me...
T = total amount of GTPase, σ = GTPase production rate. All simulation domains have periodic boundar...
<p><b>Notes:</b> The minimal models proposed here could represent the generic dynamics of protein ex...
*<p>not determined. The apparent rate constant, <i>λ</i><sub>1</sub>′, is smaller than that of photo...
Modelling human and animal metabolism is impeded by the lack of accurate quantitative parameters and...
(A)—The steady-state rate of ATP consumption by ion pumps; (B)—ATP concentration; (C)–Energy charge ...
A: Types of GTPase-based membrane patterns that occur in living cells. Some situations require the f...
<p>(A) Percentage of models that reach steady-state within 300 minutes as a function of phosphoglyce...
<p>Molecules not listed have initial concentrations of 0. All membrane bound molecules have zero con...
<p>(A) Schematic view of the three principle models. (B,D,F) The probability density function (PDF) ...
Values of the model parameters used to fit the molecular permeability and the TER model.</p
<p>Typical parameter values used in the simulations are shown. For parameters that were varied, the ...
<div><p>(A) The Rho family of GTPases, which are localized in the membrane (GTP-bound active forms) ...
<p>The asterisk represents the product between binding rates and concentration of GDI (subscripts th...
<p>A. Model for lumped variables and rates. The term in the dotted box includes effector bound GTPas...
<p>These parameters were fixed throughout our simulations.</p><p>Default parameter values for the me...
T = total amount of GTPase, σ = GTPase production rate. All simulation domains have periodic boundar...
<p><b>Notes:</b> The minimal models proposed here could represent the generic dynamics of protein ex...
*<p>not determined. The apparent rate constant, <i>λ</i><sub>1</sub>′, is smaller than that of photo...
Modelling human and animal metabolism is impeded by the lack of accurate quantitative parameters and...
(A)—The steady-state rate of ATP consumption by ion pumps; (B)—ATP concentration; (C)–Energy charge ...
A: Types of GTPase-based membrane patterns that occur in living cells. Some situations require the f...
<p>(A) Percentage of models that reach steady-state within 300 minutes as a function of phosphoglyce...
<p>Molecules not listed have initial concentrations of 0. All membrane bound molecules have zero con...
<p>(A) Schematic view of the three principle models. (B,D,F) The probability density function (PDF) ...
Values of the model parameters used to fit the molecular permeability and the TER model.</p
<p>Typical parameter values used in the simulations are shown. For parameters that were varied, the ...
<div><p>(A) The Rho family of GTPases, which are localized in the membrane (GTP-bound active forms) ...
DOI
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