Basophil develops in the absence of gp96.

<p><i>A</i>, Presence of B220⁻IgG^high basophil population (boxed) in the bone marrow of gp96 <i>KO</i> mice. <i>B</i>, Intracellular stain demonstrated an efficient deletion of gp96 in bone marrow cells of <i>Hsp90b1^floxRosa26^ERcre</i> (<i>KO</i>) mice by TAM. <i>C</i>, Both <i>WT</i> and gp96 <i>KO</i> B220⁻IgG^high basophils express FcεRI (open histogram indicates gp96 or FcεRI; shaded histogram, isotype control).