Acute EGF treatment in non-diabetic control hearts opposes the ischemia-induced changes in phosphorylation of EGFR/erbB2 signaling cascade.

<p><b>a</b>) A representative Western blot of phosphorylation changes in key molecules following acute administration of EGF before ischemia (CEP) or after ischemia (CER) is compared to control hearts subjected to 40 mins ischemia (CI); b–g) densitometry plots quantifying the relative intensity of bands for the stated molecule relative to actin. N=4; * significantly different to CI.