EGFR inhibition alters the expression levels of key cell cycle regulators.

<p>(A) The indicated human glioma cell lines were harvested and the expression levels of the indicated proteins were analyzed by western blotting with specific antibodies. (B) LN229 and T98G cells were treated with 10 µM erlotinib for the indicated time, harvested and the expression levels of the indicated proteins were analyzed by western blotting with specific antibodies. (C) As in B, but LN229, T98G and U373 cells were treated as indicated.