<p>Enzyme activity in total tissue was assessed by incubating fresh tissue sections in the presence of <sup>3</sup>H-labelled substrate corticosterone. Metabolites were separated by thin-layer chromatography. Conversion rates of <sup>3</sup>H-corticosterone (B) into <sup>3</sup>H-11-dehydrocorticosterone (A) were calculated as percentage of dpm A/(dpm A+dpm B) and expressed per area of tissue. Sham normal salt: open circles, UNX normal salt: closed circles, sham high salt: open squares, UNX high salt: closed squares. The median for each group is given by a horizontal line (n = 7).</p
Interconversion between cortisone and the glucocorticoid receptor ligand cortisol is carried out by ...
Glucocorticoid intracellular metabolism, catalyzed by the two isozymes of 11 {beta}-hydroxysteroid d...
cies in the conversion between active and inactive glucocorticoids in the kidney can lead to hyperte...
International audienceEnzymatic properties of the enzyme 11 beta-hydroxysteroid dehydrogenase (11-HS...
11-hydroxysteroid dehydrogenase (11HSD) catalyzes the conversion of the glucocorticoids, corticost...
<p>11β-HSD1 catalyzes the conversion of cortisone into cortisol in the liver or fat tissues, and 11β...
Recently the hitherto accepted concept of mechanism(s) of interaction between (cortico)steroid hormo...
A fluorometnic method for determination of the 3fl-hydroxysteroid dehydrogenase systens its microgra...
Dehydrogenation of androsterone, catalysed by both particulate and soluble fractions of rat ventral ...
The high speed supernatant of mouse liver is active in the C-20 ketone reduction of a number of vari...
Multiple patterns of 11β-hydroxysteroid dehydrogenase along the mammalian nephron. The enzyme 11β-hy...
11β-Hydroxysteroid dehydrogenase type 1 (11βHSD1) is a therapeutic target in metabolic syndrome beca...
The enzyme responsible for catalysing the oxidation-reduction of the 11-oxygen functions of steroids...
Glucocorticoids have a diverse array of functions affecting almost all tissues in the body. While ci...
11â-Hydroxysteroid dehydrogenases (11â-HSDs) inter-convert active corticosterone and inert 11-dehydr...
Interconversion between cortisone and the glucocorticoid receptor ligand cortisol is carried out by ...
Glucocorticoid intracellular metabolism, catalyzed by the two isozymes of 11 {beta}-hydroxysteroid d...
cies in the conversion between active and inactive glucocorticoids in the kidney can lead to hyperte...
International audienceEnzymatic properties of the enzyme 11 beta-hydroxysteroid dehydrogenase (11-HS...
11-hydroxysteroid dehydrogenase (11HSD) catalyzes the conversion of the glucocorticoids, corticost...
<p>11β-HSD1 catalyzes the conversion of cortisone into cortisol in the liver or fat tissues, and 11β...
Recently the hitherto accepted concept of mechanism(s) of interaction between (cortico)steroid hormo...
A fluorometnic method for determination of the 3fl-hydroxysteroid dehydrogenase systens its microgra...
Dehydrogenation of androsterone, catalysed by both particulate and soluble fractions of rat ventral ...
The high speed supernatant of mouse liver is active in the C-20 ketone reduction of a number of vari...
Multiple patterns of 11β-hydroxysteroid dehydrogenase along the mammalian nephron. The enzyme 11β-hy...
11β-Hydroxysteroid dehydrogenase type 1 (11βHSD1) is a therapeutic target in metabolic syndrome beca...
The enzyme responsible for catalysing the oxidation-reduction of the 11-oxygen functions of steroids...
Glucocorticoids have a diverse array of functions affecting almost all tissues in the body. While ci...
11â-Hydroxysteroid dehydrogenases (11â-HSDs) inter-convert active corticosterone and inert 11-dehydr...
Interconversion between cortisone and the glucocorticoid receptor ligand cortisol is carried out by ...
Glucocorticoid intracellular metabolism, catalyzed by the two isozymes of 11 {beta}-hydroxysteroid d...
cies in the conversion between active and inactive glucocorticoids in the kidney can lead to hyperte...