<i>Rabx-5</i> mutant animals age faster and RAB-5 endosomal compartments become disorganized with age.

<p>A) Survival assay indicates that <i>rabx-5</i> mutant animals age faster than wild type animals (log-rank test p<0.0001). B) P_unc-25YFP::RAB-5 expression in the soma and dorsal cord of adult day 1 and day 10 wild-type and <i>rabx-5</i> mutant animals. Synaptic intensity is more variable in adult day 10 animals (F test probability that variances differ p<0.0001). Each point represents a single soma, synaptic puncta, or intersynaptic axonal region, respectively.