PMM resistance selection in promastigotes: <i>in vitro</i> PMM susceptibility (IC<sub>50</sub>) of <i>L. donovani</i> parasites cultured as promastigotes under increasing PMM drug pressure.
- Sarah Hendrickx (321143)
- Raquel Andrea Inocêncio da Luz (321144)
- Vasundhra Bhandari (162788)
- Kristel Kuypers (321145)
- Craig D. Shaw (321146)
- Julien Lonchamp (321147)
- Poonam Salotra (162805)
- Katharine Carter (321150)
- Shyam Sundar (58354)
- Suman Rijal (181185)
- Jean-Claude Dujardin (56958)
- Paul Cos (233137)
- Louis Maes (191127)
Publication date
February 2013
DOIAbstract
<p>To determine amastigote susceptibility of the induced promastigotes, stationary-phase stages were used to infect mouse primary macrophages and J774 macrophages.</p><p> <i>P = parent non selected strain/R = selected resistant strain</i></p><p> <i>nd = not done.</i></p>*<p> <i>BPK087/0 cl-11: susceptible to Sb<sup>III</sup> (IC<sub>50</sub><15 µg/ml eq.) and resistant to Sb<sup>V</sup> (IC<sub>50</sub>>77 µg/ml eq.)</i></p
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