<p>Gene corresponds to the locus of the dominant mutation, whereas mutation corresponds to whether the individual was wild-type or mutant with respect to that locus. Mass is given in milligrams with corresponding standard error. Percent difference in mass for a given gene is expressed as the difference between wild-type (High Condition) and mutant (Low Condition) masses, divided by the mutant (Low Condition) mass. P-values for significant differences are boldfaced.</p
) polymorphisms are associated with BMI changes. polymorphisms and BMI. Weighted mean differences (W...
<p>Data are means ± standard errors of the mean. Regions where mutations have recessive effects (0< ...
Number of genes significantly changed in each treatment when compared to either the untreated sample...
Results of Mann-Whitney test for difference in load among population based on missense mutation and ...
<p>Effect size is on standardised age-adjusted SU levels. Error bars indicate the standard errors of...
Mutation is the ultimate source of genetic variability. However, a large fraction of mutations reduc...
Metabolic rate (MR) often scales with body mass (BM) following a power function of the form MR=aBMb,...
<p>Unlike letters denote significant differences (<i>P</i><0.05) across days (independent of geno...
<p>P values of the comparison of gene expression in the studied tissues between obese patients and t...
Effect of selection on BMR with (A), and without (B) correction for body mass. Data are presented as...
Metabolic rate (MR) often scales with body mass (BM) following a power function of the form MR = aBM...
Coefficients of variation observed for genes expressing at a minimum level of 10, 50, or 200 counts....
<p>This figure is a schematic showing how the distribution of fitness effects of beneficial mutation...
a<p>e.g., if the mutant gene is completely recessive for the trait and for fitness, <i>d</i> = −<i>a...
<p>Five groups of mutated genes were ranked in the top 50, 100, 150, 200 and 250 by betweenness coef...
) polymorphisms are associated with BMI changes. polymorphisms and BMI. Weighted mean differences (W...
<p>Data are means ± standard errors of the mean. Regions where mutations have recessive effects (0< ...
Number of genes significantly changed in each treatment when compared to either the untreated sample...
Results of Mann-Whitney test for difference in load among population based on missense mutation and ...
<p>Effect size is on standardised age-adjusted SU levels. Error bars indicate the standard errors of...
Mutation is the ultimate source of genetic variability. However, a large fraction of mutations reduc...
Metabolic rate (MR) often scales with body mass (BM) following a power function of the form MR=aBMb,...
<p>Unlike letters denote significant differences (<i>P</i><0.05) across days (independent of geno...
<p>P values of the comparison of gene expression in the studied tissues between obese patients and t...
Effect of selection on BMR with (A), and without (B) correction for body mass. Data are presented as...
Metabolic rate (MR) often scales with body mass (BM) following a power function of the form MR = aBM...
Coefficients of variation observed for genes expressing at a minimum level of 10, 50, or 200 counts....
<p>This figure is a schematic showing how the distribution of fitness effects of beneficial mutation...
a<p>e.g., if the mutant gene is completely recessive for the trait and for fitness, <i>d</i> = −<i>a...
<p>Five groups of mutated genes were ranked in the top 50, 100, 150, 200 and 250 by betweenness coef...
) polymorphisms are associated with BMI changes. polymorphisms and BMI. Weighted mean differences (W...
<p>Data are means ± standard errors of the mean. Regions where mutations have recessive effects (0< ...
Number of genes significantly changed in each treatment when compared to either the untreated sample...