Cholesterol‐dependent cytolysins induce rapid release of mature IL‐1β from murine macrophages in a NLRP3 inflammasome and cathepsin B‐dependent manner | ORKG Ask

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la Bastide-van Gemert, Sacha
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Westerterp, Marit
Fotakis, Panagiotis
Ouimet, Mireille
Bochem, Andrea E.
Zhang, Hanrui
Molusky, Matthew M.
Wang, Wei
Abramowicz, Sandra
la Bastide-van Gemert, Sacha
Wang, Nan
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Reilly, Muredach P.
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Tall, Alan R.

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Westerterp, Marit
Fotakis, Panagiotis
Ouimet, Mireille
Bochem, Andrea E.
Zhang, Hanrui
Molusky, Matthew M.
Wang, Wei
Abramowicz, Sandra
la Bastide-van Gemert, Sacha
Wang, Nan
Welch, Carrie L.
Reilly, Muredach P.
Stroes, Erik S.
Moore, Kathryn J.
Tall, Alan R.

August 2018

Background: The CANTOS trial (Canakinumab Antiinflammatory Thrombosis Outcome Study) showed that ant...