Reduced levels of HSF1 and Hsp70s in striata of HD knock-in mice.

<p><b>A</b>) Western blots were prepared with protein lysates from the cerebella (Cer) or striata (St) from wild-type (WT) or STHdh(Q111) knock-in mice and probed with anti-HSF1 antibodies and anti-tubulin antibodies as a loading control (left panel). Quantification of three independent Western blots. Error bars represent SDs. *p<0.07 (two-tailed t-test). <b>B</b>) Western blots were prepared with protein lysates from the cerebella (Cer) or striata (St) from wild-type (WT) or STHdh(Q111) knock-in mice and probed with anti-Hsp70 antibodies (3A3) and anti-tubulin antibodies as a loading control. Quantification of three independent Western blots. Error bars represent SDs. *p<0.07 (two-tailed t-test).