L-NNA decreases tumor blood flow in C3H animals.

<p>(A) Representative rBF time-courses in RIF tumors for a C3H and a nude mouse after L-NNA administration (represented by the dashed line at <i>t = 0</i>). (B) Box plots of blood flow changes (<b>Δ</b>BF) after L-NNA administration within animals of each strain (N = 7 each); L-NNA decreased tumor rBF within C3H (p = 0.016), but not within nude animals (p = 0.16). As with previous experiments, nude animals displayed substantial heterogeneity in <b>Δ</b>BF.