Anti- HAs antibody responses in vaccinated mice.

<p>Antibody responses to HAs in mice vaccinated previously with rRBD in combination with the r<i>Ov</i>-ASP-1 adjuvant were compared to those generated in mice after primary immunization with the HA vaccine in the presence or absence of the r<i>Ov</i>-ASP-1 adjuvant. The IgG isotype responses in individual mouse against influenza virus HAs from three virus strains were tested by ELISA at 1∶27,000 dilutions. * indicates significant difference (<i>p</i><0.05) among multiple comparisons; in particular between mice that were immunized in the presence of r<i>Ov</i>-ASP-1 vs. no adjuvant.