Expression of TRAIL receptors R1 and R2 on purified CD138⁺ and CD138⁻ RPMI8226, NCI H929 and OPM2 cells.

<p>Purified CD138⁺ and CD138⁻ cells were incubated with mouse anti-human TRAIL receptor R1 and R2 PE-conjugated monoclonal antibodies and analysed by flow cytometry to determine the percentage of labelled cells. The numbers indicate the percentage of receptor-positive cells. A, Representative histograms showing expression of R1 (a and b, thick solid lines) and R2 (c and d, thick solid lines) in CD138⁺ (a and c) and CD138⁻ RPMI8226 cells (b and d). The thin lines represent the appropriate isotype controls. B and C, Numerical representation of the percentage of CD138⁺ and CD138⁻ NCI H929 and OPM2 cells expressing R1 and R2 receptors.