Neutralizing antibody titers in mice immunized with D1ED III formulated with various adjuvants¹.

1<p>Mice were immunized with D1ED III (10 µg/dose) formulated with the indicated adjuvants three times at two-week intervals. Serum samples (n = 5) were collected on 2 weeks after the last immunization. The dengue-1 virus neutralizing capacity was determined by FRNT. The neutralizing antibody titer was calculated as the reciprocal of the highest dilution that resulted in a 50% or 80% reduction of FFU compared to control samples containing the virus alone.</p>2<p>Statistical analysis was performed by the ANOVA Bonferroni post test.</p>*<p><i>p</i><0.05 compared to PBS.</p>#<p><i>p</i><0.05 compared to Alum.</p>§<p><i>p</i><0.05 compared to CpG.</p>†<p><i>p</i><0.05 compared to PELC.