<p>Points mark the simulation results whereas lines correspond to fitted linear function From top to bottom, the following sets of constant kinetic parameters have been assumed: (a) (b) (c) Errors (standard deviation from the mean) are too small to be visible.</p
(A) Time courses of absolute and scaling values in simulation. The gray and red lines indicate negat...
<p>Model comparison and parameter estimates with 90% CI for the linear and non-linear models for all...
<p>BD simulations were not run for the spherical receptor systems, so no costs are listed. Also, bru...
<p>(<b>A</b> and <b>B</b>): Dependence of and with the tuning parameters for and . (<b>A</b>) wa...
<p>Parameters and the regression coefficients (R<sup>2</sup>) of the kinetic models.</p
Costs (in billions of €) in selected years of simulation, for individual disease stages and no chang...
<p>Figures showing the Cartesian distance between Barycentric coordinates for both the data (a) and ...
<p>Parameter estimates for the models of target cell kinetics in blood and spleen.</p
<p>NA: non applicable.</p>a<p>Parameter estimates are listed together with the corresponding coeffic...
<p>The solid line and shaded areas indicate predicted rate constant and error as a function of tempe...
<p>(A) Simulation outputs as noted for parameter sets A and B and indicated total concentrations of ...
<p>In (a) and (b) (red line), (green dashed line), (blue dotted line). All simulations done with ...
<p>(<b>A</b>) Simulation fitting result (mean (full line) ± standard deviation (area)) compared to i...
<p>(A) the ROC curves of GP4Rate and Rate4Site in the realistic simulations; (B) the losses of GP4Ra...
<p>The rate constant is set equal to <i>k</i><sub>3</sub> throughout the work, whereas , and may d...
(A) Time courses of absolute and scaling values in simulation. The gray and red lines indicate negat...
<p>Model comparison and parameter estimates with 90% CI for the linear and non-linear models for all...
<p>BD simulations were not run for the spherical receptor systems, so no costs are listed. Also, bru...
<p>(<b>A</b> and <b>B</b>): Dependence of and with the tuning parameters for and . (<b>A</b>) wa...
<p>Parameters and the regression coefficients (R<sup>2</sup>) of the kinetic models.</p
Costs (in billions of €) in selected years of simulation, for individual disease stages and no chang...
<p>Figures showing the Cartesian distance between Barycentric coordinates for both the data (a) and ...
<p>Parameter estimates for the models of target cell kinetics in blood and spleen.</p
<p>NA: non applicable.</p>a<p>Parameter estimates are listed together with the corresponding coeffic...
<p>The solid line and shaded areas indicate predicted rate constant and error as a function of tempe...
<p>(A) Simulation outputs as noted for parameter sets A and B and indicated total concentrations of ...
<p>In (a) and (b) (red line), (green dashed line), (blue dotted line). All simulations done with ...
<p>(<b>A</b>) Simulation fitting result (mean (full line) ± standard deviation (area)) compared to i...
<p>(A) the ROC curves of GP4Rate and Rate4Site in the realistic simulations; (B) the losses of GP4Ra...
<p>The rate constant is set equal to <i>k</i><sub>3</sub> throughout the work, whereas , and may d...
(A) Time courses of absolute and scaling values in simulation. The gray and red lines indicate negat...
<p>Model comparison and parameter estimates with 90% CI for the linear and non-linear models for all...
<p>BD simulations were not run for the spherical receptor systems, so no costs are listed. Also, bru...