The effect on body weight analysis of hPK5/NGR-hPK5 and cisplatin.

<p>C57BL/6J mice were injected i.p. with either PBS or cisplatin, recombinant protein alone or combined with cisplatin. On day 1 after post-treatment, the body weight was observed. <b><i>A</i></b><b>,</b> Control (PBS); <b><i>B</i></b><b>,</b> Cisplatin at 2 mg/kg/day dose every other day (6 times totally); <b><i>C</i></b><b>,</b> Cisplatin at 2 mg/kg/day dose every day (12 times totally); <b><i>D</i></b><b>,</b> hPK5 at 1.25 mg/kg/day dose every other day (6 times totally); <b><i>E</i></b><b>,</b> hPK5+cisplatin (B); <b><i>F</i></b><b>,</b> NGR-hPK5 at 1.25 mg/kg/day dose every other day (6 times totally); <b><i>G</i></b><b>,</b> NGR-hPK5+cisplatin (B). Five mice were used in each sample group, and the data shown were the mean volume ± SD. * <i>p</i><0.05 compared with control.