†<p>labeled with tetramethylrhodamine.</p>*<p><i>p</i><0.05 by <i>t</i>–test.</p>**<p><i>p</i><0.15 by <i>t–test.</i></p><p>All values are the average of at least three replicates, showing the standard deviation of each.</p
Hypertrophic cardiomyopathy (HCM) is a disease of sarco-meric proteins. The mechanism by which mutan...
Mutations in genes encoding sarcomeric proteins are the most common cause of inherited cardiomyopath...
<p>Gene expression of cardiac α-actin (<b>A</b>, <b>E</b>) and cardiac troponin T (<b>C</b>, <b>G</b...
<p>The locations of ACTC mutations associated with cardiomyopathies are shown in black (HCM) and red...
Determining the molecular mechanisms that lead to the development of heart failure will help us gain...
<p><b><i>A</i></b><i>.</i> The melting temperature of WT ACTC (•) (black circle) was similar to that...
Determining the molecular mechanisms that lead to the development of heart failure will help us gain...
Hypertrophic cardiomyopathy (HCM) is an inherited cardiovascular disease (CD) that commonly causes a...
Inherited cardiomyopathies are caused by point mutations in sarcomeric gene products, including alph...
Human wild type (wt) cardiac \(\alpha\)-actin and its mutants p.A295S or p.R312H and p.E361G correla...
<p><b><i>A</i></b><i>.</i> The protein structure of actin (PDB 1J6Z) <a href="http://www.plosone.org...
Hypertrophic and restrictive cardiomyopathies are congenital cardiac diseases that have an incidence...
The demonstrated number 1 killer in the world is cardiovascular disease, with inherited cardiomyopat...
Familial hypertrophic cardiomyopathy (HCM) is caused by mutations in at least 8 contractile protein ...
Mutations in the cardiac actin gene (ACTC1) are associated with the development of hypertrophic card...
Hypertrophic cardiomyopathy (HCM) is a disease of sarco-meric proteins. The mechanism by which mutan...
Mutations in genes encoding sarcomeric proteins are the most common cause of inherited cardiomyopath...
<p>Gene expression of cardiac α-actin (<b>A</b>, <b>E</b>) and cardiac troponin T (<b>C</b>, <b>G</b...
<p>The locations of ACTC mutations associated with cardiomyopathies are shown in black (HCM) and red...
Determining the molecular mechanisms that lead to the development of heart failure will help us gain...
<p><b><i>A</i></b><i>.</i> The melting temperature of WT ACTC (•) (black circle) was similar to that...
Determining the molecular mechanisms that lead to the development of heart failure will help us gain...
Hypertrophic cardiomyopathy (HCM) is an inherited cardiovascular disease (CD) that commonly causes a...
Inherited cardiomyopathies are caused by point mutations in sarcomeric gene products, including alph...
Human wild type (wt) cardiac \(\alpha\)-actin and its mutants p.A295S or p.R312H and p.E361G correla...
<p><b><i>A</i></b><i>.</i> The protein structure of actin (PDB 1J6Z) <a href="http://www.plosone.org...
Hypertrophic and restrictive cardiomyopathies are congenital cardiac diseases that have an incidence...
The demonstrated number 1 killer in the world is cardiovascular disease, with inherited cardiomyopat...
Familial hypertrophic cardiomyopathy (HCM) is caused by mutations in at least 8 contractile protein ...
Mutations in the cardiac actin gene (ACTC1) are associated with the development of hypertrophic card...
Hypertrophic cardiomyopathy (HCM) is a disease of sarco-meric proteins. The mechanism by which mutan...
Mutations in genes encoding sarcomeric proteins are the most common cause of inherited cardiomyopath...
<p>Gene expression of cardiac α-actin (<b>A</b>, <b>E</b>) and cardiac troponin T (<b>C</b>, <b>G</b...