Adapting to plasticity of the recurrent excitatory connection strength.

<p>Response of the recurrent network when varying the normalized strength of the recurrent excitatory connections from 0.5 up to 1.15 (see <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1002494#s4" target="_blank">Methods</a> for the standard values). A: Median firing rate of e-cells (circles) and i-cells (triangles) in the network without HSE. B: Median firing rate of e-cells (circles) and i-cells (triangles) in the network with HSE. Dotted lines at 2 and 8 Hz give target rates of both cell types. C: Population mean of the e-cells (circles) and i-cells (triangles) in the network with HSE. D: Population mean coefficient of variation of the interspike intervals (CV) of the e-cells in the network without HSE (filled circles) and in the network with HSE (open circles). E: Required ratio of adaptation time scales for stable adaptation dynamics when the network is perturbed from its adapted state (characterized in panels B and C). The perturbation consists of a 0.3 kHz step increase of the external drive to all cells in the network. The same criterium for stability of the adaptation dynamics is used as in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1002494#pcbi-1002494-g002" target="_blank">figure 2</a>.