Changes in 14-3-3 protein and PrP levels in CSF from six CJD patients overtime.

<p>PrP and 14-3-3 protein levels were analyzed in CSF samples obtained by lumbar puncture of 6 CJD patients (CJD-1 to CJD-6) at different time points during disease. Total protein content was assessed by Ponceau Red staining, the predominant band (albumin) is shown. The asterisk in samples from CJD-2, CJD-5 and CJD-6 indicates an additional PrP protein band detected between PrP band 1 and band 2.