Cellular responses of rLdPDI of <i>L. donovani</i> in human PBMCs.

<p>LTT response of PBMCs in non endemic normal/healthy individuals, endemic contacts, leishmania infected patients and cured individuals. Each bar represent the mean OD ± SD value of stimulated PBMCs of each group (A); Th1 and Th2 cytokine production (B–D) in PBMCs from individuals of cured VL patients (7) and endemic controls (5) in response to rLdPDI and SLD antigens, each data point represents one individual. Values are given as concentration in pg/ml. The statistical significances are given between infected vs cured and infected vs endemic individuals. (*, p<0.05; **, p<0.01; and ***, p<0.001).