System overview of the proposed optimization framework.

<p>The software requires access to a library of characterized parts (such as a subset of the parts available in Parts Registry) that will be used as fundamental blocks in the synthetic circuit. The user will have to supply a specific design (static connectivity), together with a set of constraints and a specific objective function to be optimized. The software will translate this system to a set of linear constraints that it will subsequently solve. The result of the optimization framework will be the set of parts that have to be used, and at what position. The system will have the ability to simulate the proposed design, and provide candidate synthetic circuits for experimental construction in the laboratory.