LPS-induced TNF-α, MCP-1 and IL-6 mRNA expression in primary rat microglia after treatment with IκB-α siRNA.

<p>IκB-α protein expression in primary rat microglia transfected with IκB-α siRNA for 48 h (A). The effects of artemisinin on LPS-induced TNF-α (B), MCP-1 (C) and IL-6 (D) mRNA expression in cultured cells after incubation with IκB-α siRNA for 48 h. The data are presented as the means±S.E.M. from five separate experiments. *P<0.05 vs. control, ^#P<0.05 vs. treatment with LPS alone, and ^$P<0.05 vs. treatment with LPS and artemisinin.