Changes in RAGE expression on activated T cells from patients with T1D and healthy control subjects.

<p>RAGE expression was studied on CD4+ or CD8+ T cells before and 48 hrs after culture with anti-CD3 mAb. RAGE expression was higher on CD4+ (p<0.001) and CD8+ (p<0.001) T cells from patients with T1D vs healthy controls. While the level of RAGE expression increased in CD4+ and CD8+ T cells from healthy control subjects (p<0.05), it decreased in the patients with T1D (p<0.05).