<p>A, [Ca<sup>2+</sup>]<sub>i</sub> recording of an islet of Langerhans in the presence of 8 mM glucose; 10 nM STX was added to the perfusion when indicated; n = 11 islets from 3 different male mice. B, [Ca<sup>2+</sup>]<sub>i</sub> recording of an isolated pancreatic β-cell in the presence of 8 mM glucose; 10 nM STX was added to the perfusion when indicated. C, Area under the curve in [Ca<sup>2+</sup>]<sub>i</sub> recordings from isolated β-cells. * p<0.000005; n = 100 cells from 3 different male mice.</p
Indiana University-Purdue University Indianapolis (IUPUI)Type 2 diabetes mellitus is a chronic disor...
<p>A, Intraperitoneal glucose tolerance test (IPGTT) in ovariectomized female mice after one single ...
The mechanisms of glucagon secretion and its suppression by glucose are presently unknown. This stud...
<p>A, Measurement of insulin secretion in isolated islets from male mice at different STX concentrat...
The non-steroidal compound STX modulates the hypothalamic control of core body temperature and energ...
<p>(A) Overview of calcium imaging method for islets: intact islets were plated on a 96 well plate. ...
Pancreatic islet hormones regulate blood glucose homeostasis. Changes in blood glucose induce oscill...
<p>Gray and black traces represent α- and β-cells, respectively. A, representative intracellular cal...
<p>A, representative intracellular calcium responses to blockade of N- and L-type calcium channels. ...
<p>(<b>A</b>) Representative [Ca<sup>2+</sup>]<sub>cyt</sub> tracings in islets isolated from WT and...
Studying the response of islet cells to glucose stimulation is important for understanding cell func...
<p>A, Body weight in male mice before and after the 6 day-treatment with either vehicle or STX; n = ...
Studying the response of islet cells to glucose stimulation is important for understanding cell func...
<p>A, Intraperitoneal glucose tolerance test (IPGTT) in male mice after injection of Vehicle (•) or ...
Studying the response of islet cells to glucose stimulation is important for understanding cell func...
Indiana University-Purdue University Indianapolis (IUPUI)Type 2 diabetes mellitus is a chronic disor...
<p>A, Intraperitoneal glucose tolerance test (IPGTT) in ovariectomized female mice after one single ...
The mechanisms of glucagon secretion and its suppression by glucose are presently unknown. This stud...
<p>A, Measurement of insulin secretion in isolated islets from male mice at different STX concentrat...
The non-steroidal compound STX modulates the hypothalamic control of core body temperature and energ...
<p>(A) Overview of calcium imaging method for islets: intact islets were plated on a 96 well plate. ...
Pancreatic islet hormones regulate blood glucose homeostasis. Changes in blood glucose induce oscill...
<p>Gray and black traces represent α- and β-cells, respectively. A, representative intracellular cal...
<p>A, representative intracellular calcium responses to blockade of N- and L-type calcium channels. ...
<p>(<b>A</b>) Representative [Ca<sup>2+</sup>]<sub>cyt</sub> tracings in islets isolated from WT and...
Studying the response of islet cells to glucose stimulation is important for understanding cell func...
<p>A, Body weight in male mice before and after the 6 day-treatment with either vehicle or STX; n = ...
Studying the response of islet cells to glucose stimulation is important for understanding cell func...
<p>A, Intraperitoneal glucose tolerance test (IPGTT) in male mice after injection of Vehicle (•) or ...
Studying the response of islet cells to glucose stimulation is important for understanding cell func...
Indiana University-Purdue University Indianapolis (IUPUI)Type 2 diabetes mellitus is a chronic disor...
<p>A, Intraperitoneal glucose tolerance test (IPGTT) in ovariectomized female mice after one single ...
The mechanisms of glucagon secretion and its suppression by glucose are presently unknown. This stud...