<p>A, Body weight in male mice before and after the 6 day-treatment with either vehicle or STX; n = 5 mice/condition. B, Fasting glycemia in the following morning after the 6-day treatment with vehicle or STX treated mice (n = 5 mice/condition). C, IPGTT in the same mice as in B; vehicle (•), STX (○); n = 4–5 mice/condition. D, Insulin content in isolated islets from vehicle and STX-treated mice; n = 60–120 islets from 2–3 mice/condition.</p
<p>(A, D) No significant change was observed on blood glucose levels during the OGTT between vehicle...
Caloric restriction (CR) is the only environmental intervention with robust evidence that it extends...
<p>(<b><i>A</i></b>) STZ injection in both 4 months old wild-type (WT) and pR5 mice induces chronica...
<p>A, Intraperitoneal glucose tolerance test (IPGTT) in ovariectomized female mice after one single ...
<p>A, Plasma insulin concentration (µg/l) measured at 30 min after a 2 g/kg glucose load in male mic...
<p>A, IPGTT in control mice or treated with nicotinamide and streptozotocin (STZ) to generate glucos...
<p>A, Measurement of insulin secretion in isolated islets from male mice at different STX concentrat...
<p>A, Intraperitoneal glucose tolerance test (IPGTT) in male mice after injection of Vehicle (•) or ...
The non-steroidal compound STX modulates the hypothalamic control of core body temperature and energ...
<p>Mice received the indicated sample treatments for 5 weeks. Diabetes was induced by multiple (for ...
<p>(<i>A</i>) Western blot analysis of hemibrain lysates from vehicle- and STZ-treated 5XFAD mice. (...
<p>A. Blood glucose levels of control and diabetic mice are shown as a function of time after the in...
A.) After HFD, fl/fl (dark bars) and MX1-Δ (open bars) male mice were injected with glucose (2 g/kg ...
<p>Adult C57BL/6 mice were treated with STZ at a dose of 130 mg/kg body weight via i.p. injection, m...
Clinical studies suggest that short-term insulin treatment in new-onset type 2 diabetes (T2DM) can p...
<p>(A, D) No significant change was observed on blood glucose levels during the OGTT between vehicle...
Caloric restriction (CR) is the only environmental intervention with robust evidence that it extends...
<p>(<b><i>A</i></b>) STZ injection in both 4 months old wild-type (WT) and pR5 mice induces chronica...
<p>A, Intraperitoneal glucose tolerance test (IPGTT) in ovariectomized female mice after one single ...
<p>A, Plasma insulin concentration (µg/l) measured at 30 min after a 2 g/kg glucose load in male mic...
<p>A, IPGTT in control mice or treated with nicotinamide and streptozotocin (STZ) to generate glucos...
<p>A, Measurement of insulin secretion in isolated islets from male mice at different STX concentrat...
<p>A, Intraperitoneal glucose tolerance test (IPGTT) in male mice after injection of Vehicle (•) or ...
The non-steroidal compound STX modulates the hypothalamic control of core body temperature and energ...
<p>Mice received the indicated sample treatments for 5 weeks. Diabetes was induced by multiple (for ...
<p>(<i>A</i>) Western blot analysis of hemibrain lysates from vehicle- and STZ-treated 5XFAD mice. (...
<p>A. Blood glucose levels of control and diabetic mice are shown as a function of time after the in...
A.) After HFD, fl/fl (dark bars) and MX1-Δ (open bars) male mice were injected with glucose (2 g/kg ...
<p>Adult C57BL/6 mice were treated with STZ at a dose of 130 mg/kg body weight via i.p. injection, m...
Clinical studies suggest that short-term insulin treatment in new-onset type 2 diabetes (T2DM) can p...
<p>(A, D) No significant change was observed on blood glucose levels during the OGTT between vehicle...
Caloric restriction (CR) is the only environmental intervention with robust evidence that it extends...
<p>(<b><i>A</i></b>) STZ injection in both 4 months old wild-type (WT) and pR5 mice induces chronica...