Activation of Sirt1 inhibits resistin expression in macrophages.

<p><b>A</b>, Sirt1 and resistin mRNA levels in U937 macrophages treated for 24 h with LPS (1 µg/mL) and resveratrol (50 µM) or their respective vehicle. <b>B</b>, Secreted levels of resistin in U937 macrophages treated as in A. Bars are representative of 3 experiments done in triplicate. In all panels, * indicates a significant difference between groups.