Detection of the percentage of CD4<sup>+</sup>CD127<sup>low+/−</sup>FoxP3<sup>+</sup>-Treg cells of total CD4<sup>+</sup>-T cells in rejecting and non-rejecting patients after kidney transplantation.
- Matthias Schaier (328354)
- Nicole Seissler (328355)
- Edgar Schmitt (24047)
- Stefan Meuer (328356)
- Friederike Hug (328357)
- Martin Zeier (190503)
- Andrea Steinborn (328358)
Publication date
February 2013
DOIAbstract
<p>The percentage of CD4<sup>+</sup>CD127<sup>low+/−</sup>FoxP3<sup>+</sup>-Tregs of total CD4<sup>+</sup>-T cells was estimated in healthy non-transplanted volunteers (▴), in kidney transplant patients with stable transplant function (♦) and in kidney transplant patients with biopsy proven rejection (BPR), (•). The percentage of CD4<sup>+</sup>CD127<sup>low+/−</sup>FoxP3<sup>+</sup>-Tregs decreased continuously after transplantation. Significant differences between rejecting and non-rejecting patients were not detected.</p
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