<p>Each longitudinal protofilament of an MT is made up of α and β tubulin subunit heterodimers. Assembly of MTs depends on addition of ‘GTP-tubulin’. Top, right: blue dimers with both exchangeable and non-exchangeable sites occupied by GTP will continue to add to assembling MTs. Bottom, right: dimers at MT edge which hydrolyze GTP to GDP flex and separate protofilaments from MT, curved protofilaments resembling ‘rams horns’.</p
<div><p>Microtubules are long filamentous hollow cylinders whose surfaces form lattice structures of...
Microtubules are highly dynamic cytoskeletal fibers essential for the cell’s life. Their dynamics is...
Microtubules exist in dynamic equilibrium, growing and shrinking by the addition or loss of tubulin ...
<p>(A) Tubulin dimer. Light grey –α-tubulin, Dark Grey – β-tubulin. C-terminal tails extend from the...
Thirteen tubulin protofilaments, made of αβ-tubulin heterodimers, interact laterally to produce cyto...
Thirteen tubulin protofilaments, made of αβ-tubulin heterodimers, interact laterally to produce cyto...
International audienceMicrotubules are cytoskeletal components involved in pivotal eukaryotic functi...
In the presence of GTP, purified dimers of alpha- and beta-tubulin will interact longitudinally and ...
SummaryMicrotubules (MTs) polymerize via net addition of GTP-tubulin subunits to the MT plus end, wh...
International audienceMicrotubule growth proceeds through the endwise addition of nucleotide-bound t...
Microtubules are structural elements of eukaryotic cells which are important for cell motility, cell...
Microtubules (MTs) are key components of the cytoskeleton and play a central role in cell division a...
SummaryRecent work describes the surprising finding that cellular microtubules have islands of GTP-b...
SummaryMicrotubules exist in dynamic equilibrium, growing and shrinking by the addition or loss of t...
International audienceMicrotubules are tubes of about 25 nm in diameter that are critically involved...
<div><p>Microtubules are long filamentous hollow cylinders whose surfaces form lattice structures of...
Microtubules are highly dynamic cytoskeletal fibers essential for the cell’s life. Their dynamics is...
Microtubules exist in dynamic equilibrium, growing and shrinking by the addition or loss of tubulin ...
<p>(A) Tubulin dimer. Light grey –α-tubulin, Dark Grey – β-tubulin. C-terminal tails extend from the...
Thirteen tubulin protofilaments, made of αβ-tubulin heterodimers, interact laterally to produce cyto...
Thirteen tubulin protofilaments, made of αβ-tubulin heterodimers, interact laterally to produce cyto...
International audienceMicrotubules are cytoskeletal components involved in pivotal eukaryotic functi...
In the presence of GTP, purified dimers of alpha- and beta-tubulin will interact longitudinally and ...
SummaryMicrotubules (MTs) polymerize via net addition of GTP-tubulin subunits to the MT plus end, wh...
International audienceMicrotubule growth proceeds through the endwise addition of nucleotide-bound t...
Microtubules are structural elements of eukaryotic cells which are important for cell motility, cell...
Microtubules (MTs) are key components of the cytoskeleton and play a central role in cell division a...
SummaryRecent work describes the surprising finding that cellular microtubules have islands of GTP-b...
SummaryMicrotubules exist in dynamic equilibrium, growing and shrinking by the addition or loss of t...
International audienceMicrotubules are tubes of about 25 nm in diameter that are critically involved...
<div><p>Microtubules are long filamentous hollow cylinders whose surfaces form lattice structures of...
Microtubules are highly dynamic cytoskeletal fibers essential for the cell’s life. Their dynamics is...
Microtubules exist in dynamic equilibrium, growing and shrinking by the addition or loss of tubulin ...