<p>Comparison of model simulations and experimental evidence representing <i>HSP90</i> mRNA levels during thermal upshifts. (A) Model simulations of the dynamic changes in <i>HSP90</i> mRNA levels following heat shock: grey line 30°C–37°C, black line: 30°C–42°C. (B) Graphical illustration of experimentally determined <i>HSP90</i> mRNA levels following heat shock generated in experiments such as those shown in (C) and (D): grey line 30°C–37°C, black line: 30°C–42°C. (C) qRT-PCR quantification of <i>HSP90</i> mRNA levels relative to the internal <i>ACT1</i> mRNA control were analysed during a 30°C–37°C heat shock. (D) qRT-PCR quantification of <i>HSP90</i> mRNA levels relative to the internal <i>ACT1</i> mRNA control were analysed during a 30...
<p>Heat map showing relative expression of 186 genes that exhibited significant change in gene expre...
<p>B16F10 cells were either treated/or not with NSC or 2-Brp for 2 h or 30 min, respectively, and th...
Classic semiquantitative proteomic methods have shown that all organisms respond to a mild heat shoc...
<p>Comparison of model simulations and experimental evidence depicting Hsf1activation during heat sh...
AbstractThe heat-shock response is a key factor in diverse stress scenarios, ranging from hypertherm...
<p>The model was used to simulate sequential 30 minute heat shocks of 30°C–42°C separated either by ...
<p>The model accurately fits the WT data; moreover, it predicts a slightly delayed and attenuated re...
We studied the dynamics of the Heat Shock Response (HSR) mechanism, and the persistence of a injury-...
<p>(A) Upper panels: Representative immunoblots of Hsp70 protein in undifferentiated (-NGF) and diff...
<p>The model was used to simulate stepwise thermal transitions from 30°C (the starting condition) to...
<p>(A) RT-PCR analysis of <i>hsp70</i>, <i>hsp27</i> and splicing of <i>xbp1</i> (p, pre-sliced; s, ...
<p><b>Copyright information:</b></p><p>Taken from "Dynamic resolution of functionally related gene s...
<p>Inductions of hsp70 (A) and sat III transcripts (B) were quantified by RT-QPCR before (-) and aft...
One of the most important questions in cell biology is how cell fate is determined when exposed to e...
Increased intracellular heat shock protein-72 (Hsp72), and -90α (Hsp90α) have been implicated as imp...
<p>Heat map showing relative expression of 186 genes that exhibited significant change in gene expre...
<p>B16F10 cells were either treated/or not with NSC or 2-Brp for 2 h or 30 min, respectively, and th...
Classic semiquantitative proteomic methods have shown that all organisms respond to a mild heat shoc...
<p>Comparison of model simulations and experimental evidence depicting Hsf1activation during heat sh...
AbstractThe heat-shock response is a key factor in diverse stress scenarios, ranging from hypertherm...
<p>The model was used to simulate sequential 30 minute heat shocks of 30°C–42°C separated either by ...
<p>The model accurately fits the WT data; moreover, it predicts a slightly delayed and attenuated re...
We studied the dynamics of the Heat Shock Response (HSR) mechanism, and the persistence of a injury-...
<p>(A) Upper panels: Representative immunoblots of Hsp70 protein in undifferentiated (-NGF) and diff...
<p>The model was used to simulate stepwise thermal transitions from 30°C (the starting condition) to...
<p>(A) RT-PCR analysis of <i>hsp70</i>, <i>hsp27</i> and splicing of <i>xbp1</i> (p, pre-sliced; s, ...
<p><b>Copyright information:</b></p><p>Taken from "Dynamic resolution of functionally related gene s...
<p>Inductions of hsp70 (A) and sat III transcripts (B) were quantified by RT-QPCR before (-) and aft...
One of the most important questions in cell biology is how cell fate is determined when exposed to e...
Increased intracellular heat shock protein-72 (Hsp72), and -90α (Hsp90α) have been implicated as imp...
<p>Heat map showing relative expression of 186 genes that exhibited significant change in gene expre...
<p>B16F10 cells were either treated/or not with NSC or 2-Brp for 2 h or 30 min, respectively, and th...
Classic semiquantitative proteomic methods have shown that all organisms respond to a mild heat shoc...