Serum CAXII levels in patients with lung cancer and healthy controls in the training set.

<p>Serum CAXII levels in patients with lung cancer and healthy controls. (A) The median CAXII level in the sera from healthy controls was 0.29, and that in sera from lung cancer patients was 1.52. Serum CAXII levels were significantly higher in lung cancer patients (*P<0.001). Furthermore, serum CAXII levels were higher in SCCs than ADs (**P = 0.0381). (B) Receiver-operating characteristic curve analysis of CAXII as a serum marker for lung cancer. The corresponding areas under the curves were 0.794 for CAXII. With a 70.0% specificity, the sensitivity of CAXII for lung cancer was 82.9%, at a cut-off value corresponding to 0.387.