<p>Immunofluorescence miscroscopy of bladder sections showing SAA1/2 (red) levels and distribution in sham-infected (PBS-treated) mice (A) and mice that were infected for either one (B) or four days (C) via intravesical instillation of the UPEC isolate UTI89. (D and E) Localization of UPEC (green) with host cell nuclei (blue) and SAA1/2 at 4 d post - inoculation of the bladder with UTI89. Large arrows point to the apical membrane of urothelium and bars mark the border between urothelium and lamina propria. Small arrows indicate a few bacteria that do not co-localize with SAA1/2.</p
ABSTRACT Infection with uropathogenic Escherichia coli (UPEC), the causative agent of most uncomplic...
The in-vivo mouse bladder model was sought to determine the effect of virulent uropathogenic E. coli...
<p>(<b>A</b>) 24-hour micturition frequencies were significantly higher 5 weeks after immunization o...
<p>Four mice were either sham inoculated with PBS alone or infected with UTI89 via catheterization t...
<p>Four mice were inoculated with UTI89 via either (A) transurethral catheterization or (B) IP injec...
<p>The bladder urothelium (A) is a pseudostratified transitional epithelium lined by large facet cel...
<p>(<b>A</b>) Level of Hif-1 transcripts in bladders of HIF-1<sup>-/-</sup> (<i>Hif1αflox/flox</i>/K...
<p>Female C57Bl/6 mice were instilled with UTI89-RFP and bladders were processed for flow cytometry ...
<p>(<b>A</b>) Hematoxylin and eosin stained bladder sections taken from UPK3A 65-84-immunized mice s...
<p>(A–H) Adult female CBA/J mice were infected via catheterization with equal numbers of wild type C...
<p>Adeno-Cre (8.46×10<sup>8</sup> pfu per mouse) was delivered into the bladder lumen of ROSA mice f...
<p>(<b>A, B</b>) ELISA analysis shows pro-inflammatory cytokines IL-6, IL-1β or KC in the bladders o...
Serum amyloid A (SAA) is an acute phase protein involved in the homeostasis of inflammatory response...
<p>Adult female CBA/J mice were inoculated with UTI89 via transurethral catheterization or left unin...
<p>Macrophages were depleted or not and mice were infected. Twenty-four hours post-primary infection...
ABSTRACT Infection with uropathogenic Escherichia coli (UPEC), the causative agent of most uncomplic...
The in-vivo mouse bladder model was sought to determine the effect of virulent uropathogenic E. coli...
<p>(<b>A</b>) 24-hour micturition frequencies were significantly higher 5 weeks after immunization o...
<p>Four mice were either sham inoculated with PBS alone or infected with UTI89 via catheterization t...
<p>Four mice were inoculated with UTI89 via either (A) transurethral catheterization or (B) IP injec...
<p>The bladder urothelium (A) is a pseudostratified transitional epithelium lined by large facet cel...
<p>(<b>A</b>) Level of Hif-1 transcripts in bladders of HIF-1<sup>-/-</sup> (<i>Hif1αflox/flox</i>/K...
<p>Female C57Bl/6 mice were instilled with UTI89-RFP and bladders were processed for flow cytometry ...
<p>(<b>A</b>) Hematoxylin and eosin stained bladder sections taken from UPK3A 65-84-immunized mice s...
<p>(A–H) Adult female CBA/J mice were infected via catheterization with equal numbers of wild type C...
<p>Adeno-Cre (8.46×10<sup>8</sup> pfu per mouse) was delivered into the bladder lumen of ROSA mice f...
<p>(<b>A, B</b>) ELISA analysis shows pro-inflammatory cytokines IL-6, IL-1β or KC in the bladders o...
Serum amyloid A (SAA) is an acute phase protein involved in the homeostasis of inflammatory response...
<p>Adult female CBA/J mice were inoculated with UTI89 via transurethral catheterization or left unin...
<p>Macrophages were depleted or not and mice were infected. Twenty-four hours post-primary infection...
ABSTRACT Infection with uropathogenic Escherichia coli (UPEC), the causative agent of most uncomplic...
The in-vivo mouse bladder model was sought to determine the effect of virulent uropathogenic E. coli...
<p>(<b>A</b>) 24-hour micturition frequencies were significantly higher 5 weeks after immunization o...