<p>For <i>hENT1</i> gene, no changes were observed in H3K4m3 methylation but H3K9me2 mildly increased in the resistant cells and decreased after hydralazine treatment. In <i>dCK</i> gene there was a slight reduction in H3K4me3 in the resistant cells which was not modified by hydralazine. The methylation at H3K9me2 mildly increased in resistant cells and reduced after hydralazine. The changes in band intensity were normalized against their respective inputs.</p
The most well-studied function of DNA methylation in eukaryotic cells is the transcriptional silenci...
<p>(A) Commassie-stained gel of purified histones from the indicated strains (top) and western blots...
Histone modifications are involved in the DNA damage response (DDR). Here, by utilizing an ELISA imm...
<p>A. Quantitative RT-PCR of <i>G9A</i> shows that resistant CaLoGR cells had an increase as compare...
<p>MetaDrug™ program predicted that hydralazine may affect not only DNA methylation in cytosine but ...
BACKGROUND: Down regulation of genes coding for nucleoside transporters and drug metabolism responsi...
Down regulation of genes coding for nucleoside transporters and drug metabolism responsible for upta...
AbstractChemicals that affect cellular differentiation through epigenetic mechanisms have potential ...
Abstract Background The antihypertensive compound hydralazine is a known demethylating agent. This p...
<p>(A) MV4-11 cells were treated with 3 µM SYC-522 and (B) MOLM13 cells were treated with 10 µM SYC-...
<p>As analyzed by Western blotting, all three methylation states (mono- di- and tri-methylation) of ...
<p>Individual KDM3 subfamily members were transiently overexpressed in U-2 OS cells. (A-M) DAPI stai...
The azanucleotides azacitidine and decitabine have been shown to induce hematologic response and pro...
'To whom correspondence should be addressed Hydrazine, which is toxic and carcinogenic to roden...
<p>The genes that experienced >20 fold change in methylation after different <i>in vivo</i> treatmen...
The most well-studied function of DNA methylation in eukaryotic cells is the transcriptional silenci...
<p>(A) Commassie-stained gel of purified histones from the indicated strains (top) and western blots...
Histone modifications are involved in the DNA damage response (DDR). Here, by utilizing an ELISA imm...
<p>A. Quantitative RT-PCR of <i>G9A</i> shows that resistant CaLoGR cells had an increase as compare...
<p>MetaDrug™ program predicted that hydralazine may affect not only DNA methylation in cytosine but ...
BACKGROUND: Down regulation of genes coding for nucleoside transporters and drug metabolism responsi...
Down regulation of genes coding for nucleoside transporters and drug metabolism responsible for upta...
AbstractChemicals that affect cellular differentiation through epigenetic mechanisms have potential ...
Abstract Background The antihypertensive compound hydralazine is a known demethylating agent. This p...
<p>(A) MV4-11 cells were treated with 3 µM SYC-522 and (B) MOLM13 cells were treated with 10 µM SYC-...
<p>As analyzed by Western blotting, all three methylation states (mono- di- and tri-methylation) of ...
<p>Individual KDM3 subfamily members were transiently overexpressed in U-2 OS cells. (A-M) DAPI stai...
The azanucleotides azacitidine and decitabine have been shown to induce hematologic response and pro...
'To whom correspondence should be addressed Hydrazine, which is toxic and carcinogenic to roden...
<p>The genes that experienced >20 fold change in methylation after different <i>in vivo</i> treatmen...
The most well-studied function of DNA methylation in eukaryotic cells is the transcriptional silenci...
<p>(A) Commassie-stained gel of purified histones from the indicated strains (top) and western blots...
Histone modifications are involved in the DNA damage response (DDR). Here, by utilizing an ELISA imm...