<p>Percentages of CD4<sup>+</sup> cells bearing activation markers: CD4<sup>+</sup>CD69<sup>+</sup> (A) and CD4<sup>+</sup>HLA-DR<sup>+</sup> (B) ex vivo are significantly elevated in the group of high responders (high) in comparison with low responders (low). No differences exist concerning CD4<sup>+</sup>CD25<sup>+</sup> percentage between two investigated groups (C). Data are presented as medians, 25<sup>th</sup> and 75<sup>th</sup> percentiles and minimal/maximal values. Statistically significant differences are marked with * (P = <0,05).</p
<div><p>The identification and study of antigen-specific CD4 T cells, both in peripheral blood and i...
<p>Arrows connect the type of responder (high vs. low) with expected response to stimulation. Dotted...
<p>Human CD4<sup>+</sup> T cells isolated from the spleen of humanized mice (A and C, n = 8) and the...
<p>(1) n = 33 patients and 27 controls from both surveys.</p><p>(2) n = 16 patients and 14 controls ...
Comparison of the percentage of (A) CD4+ and (B) CD8+ T cells expressing HLA-DR, Ki-67, CD38, and CD...
<p>Extracellular staining revealed that baseline activation levels varied significantly between full...
<p>Quantitative variables are expressed as median (interquartile range).</p><p>Lymphocyte and monocy...
<p>Freezed/thawed antigens of <i>L. major</i> were used to stimulate the PBMCs in culture as previou...
<p>The expression level of activation markers CD38 and HLA-DR were compared between VP group (square...
<p>One week after the last immunization, spleen cells from IT/Saline, IT/rSm22.6, IT/rSm29, rSm22.6 ...
<p>(A) Proportion of activated circulating HLA-DR+CR38+ CD4+ T cells. (B) Proportion of activated ci...
<p>Cytokine concentrations in plasma at M0 have been plotted against CD4<sup>+</sup> T cell counts a...
<p>Activated cells were considered those expressing high levels of CD38 (CD38 bright) and MHC class ...
<p>Comparison of pre- and post-treatment frequencies of lymphocytes, CD4 T cells and T regulatory ce...
<p>The frequencies of a range of T lymphocyte subsets in the isolated PBMC populations were measured...
<div><p>The identification and study of antigen-specific CD4 T cells, both in peripheral blood and i...
<p>Arrows connect the type of responder (high vs. low) with expected response to stimulation. Dotted...
<p>Human CD4<sup>+</sup> T cells isolated from the spleen of humanized mice (A and C, n = 8) and the...
<p>(1) n = 33 patients and 27 controls from both surveys.</p><p>(2) n = 16 patients and 14 controls ...
Comparison of the percentage of (A) CD4+ and (B) CD8+ T cells expressing HLA-DR, Ki-67, CD38, and CD...
<p>Extracellular staining revealed that baseline activation levels varied significantly between full...
<p>Quantitative variables are expressed as median (interquartile range).</p><p>Lymphocyte and monocy...
<p>Freezed/thawed antigens of <i>L. major</i> were used to stimulate the PBMCs in culture as previou...
<p>The expression level of activation markers CD38 and HLA-DR were compared between VP group (square...
<p>One week after the last immunization, spleen cells from IT/Saline, IT/rSm22.6, IT/rSm29, rSm22.6 ...
<p>(A) Proportion of activated circulating HLA-DR+CR38+ CD4+ T cells. (B) Proportion of activated ci...
<p>Cytokine concentrations in plasma at M0 have been plotted against CD4<sup>+</sup> T cell counts a...
<p>Activated cells were considered those expressing high levels of CD38 (CD38 bright) and MHC class ...
<p>Comparison of pre- and post-treatment frequencies of lymphocytes, CD4 T cells and T regulatory ce...
<p>The frequencies of a range of T lymphocyte subsets in the isolated PBMC populations were measured...
<div><p>The identification and study of antigen-specific CD4 T cells, both in peripheral blood and i...
<p>Arrows connect the type of responder (high vs. low) with expected response to stimulation. Dotted...
<p>Human CD4<sup>+</sup> T cells isolated from the spleen of humanized mice (A and C, n = 8) and the...