AMJ induced selective pro-apoptotic effects in different human leukemia cells and human primary lymphoblastic leukemia cells.

<p>(A) Pro-apoptotic effect of AMJ was assessed on various human leukemia cells (HSB-2, Molt-4 and CCRF-CEM). Values are shown as means ± S.E.M. (n = 3); *, <i>P<0.05</i> versus respective control; (B) The apoptosis rate of untreated or AMJ-treated primary T-lymphocytes from 3 healthy subjects or lymphoblastic leukemia cells from 3 patients was assessed by flow cytometry using the annexin V-FITC/PI apoptosis assay. The bar graph shows the cumulative percentage of cells which are in apoptosis.