NO differentially modulates expressed Ca_Vs, potentiating L (Ca_V1) and P/Q-type (Ca_V2.1).

<p><b>A-Di</b>, Raw traces of pharmacologically isolated currents (+R-type) in <b>A-Ci</b> (black trace), and the same current from cells treated with SNP (red). Traces generated by depolarising steps from −90 mV to −10 mV (holding potential of −60 mV). <b>Aii–Dii</b>, Average IVs of control (black circles) and SNP-treated (red circles) neurons. <b>Aiii–Diii</b>, Summary bar graph showing mean inactivation kinetics (τ) of currents in control (black) and SNP-treated (red) conditions. <b>Aiv–Div</b>, Mean activation curves of currents recorded from untreated (black) and SNP-treated (red) cells. Curves are fitted to conductances applying a Boltzmann equation.