Paradigmatical reduced datasets.

<p>Following reduction of the full dataset containing diffusion values from the 130,394 voxels in the white matter skeleton, to the top 500 voxels that distinguishes between control, MCIna and MCIa subjects, this figure shows representative scatter plots from one control subject (green), one MCIna subject (orange) and one MCIa subject (red). The diffusion values for the top 500 voxels from each diffusion index are plotted. Loess regression lines (span = 2/3, polynomial degree = 1) have been fitted through each subject's dataset. For FA, the loess regression line through the data points of the control subject are seen as higher than the loess lines through the data points from MCIa or MCIna subjects. The reverse is the case for DA, DR and MD, with the loess lines through MCIa subjects indicating higher values than the lines through MCIna or control loess lines. Outliers are excluded from these graphs. For the loess line, the span which determines smoothness was set to 0.66.