Phosphorylation of SREBP-1a influences fatty acid composition of liver and serum.

<p>In liver tissues the composition total fatty acid (TFA) (<b>A</b>) and in serum samples of the same animals the composition of free fatty acid (FFA) (<b>B</b>) of C57Bl6, alb-SREBP1aΔP as well as alb-SREBP-1a transgenic animals was determined by GC analyses. Data were calculated as percent of in TFA or FFA. The graphs indicate the percental difference the values determined for alb-SREBP-1aΔP and alb-SREBP-1a mice to C57Bl6 mice. Data are given as means including standard deviation (±SD) of (n = 20) replicates per genotype (*p<0.01: alb-SREBP-1aΔP or alb-SREBP-1a vs. C57Bl6; ‡p<0.01: alb-SREBP-1aΔP vs. alb-SREBP-1a).