Metabolic changes in fish over time.

<p><b>A</b>. The ratio of triglycerides to cholesterol in blood serum of Crucian carp (<i>Carassius carassius</i>) exposed (filled bars) and not exposed (white bars) to food containing polystyrene nanoparticles. Each bar shows the average over 4 fishes. <b>B</b>. Mean distribution (± average deviation) of cholesterol (µg/mg) in liver (y-axis) and muscle (x-axis) of Crucian carp (<i>Carassius carassius</i>) over four fishes per data point. Black symbols denote nanoparticle-exposed and white symbols denote control fish. <b>C</b>. The average weight change at each time point relative to the preceding time point is shown (for day 15 relative to day -4). Filled bars refer to the nanoparticle-exposed fish and white bars to the control group. The bars show averages over 16, 12, 8 and 3 control fish, or 16, 12, 8 and 2 test fish, at day 15, 21, 27 and 39, respectively.